Deleting PDFs without affecting Mind Map

I have a bunch of PDFs saved on my iPad (in “Files”) that I then imported into MarginNote and annotated, etc. When I imported them, a duplicate file seems to have been automatically saved on my iPad (also in the “Files”). I’d like to clear out some of these PDFs and am hoping someone can tell me if I can delete either the original pdf and/or the copy MarginNote made and saved to Files without deleting the annotated pdf that I’m using within a MarginNote mind map? Thanks.